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The Historic Center of Florence is on the list of the World Heritage Sites of UNESCO: "Florence, the symbol of the Renaissance, rose to economic and cultural pre-eminence under the Medici in the 15th and 16th centuries. Its 600 years of extraordinary artistic activity can be seen above all in the 13th-century cathedral (Santa Maria del Fiore), the Church of Santa Croce, the Uffizi and the Pitti Palace, the work of great masters such as Giotto, Brunelleschi, Botticelli and Michelangelo" (quote from whc.unesco.org/en/list/174). In addition, the Boboli Gardens are one of the 12 Medici villas added to the World Heritage list.